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Semaglutide 10 mg vial: mixing & syringe guide

FDA-approved drugMetabolic & weight

How much bacteriostatic water to add to a 10 mg Semaglutide vial, what each mark on a U-100 insulin syringe holds, and how long the vial lasts at your dose.

Prescription pens come ready to use and are never mixed. This guide is only for powder vials that need water added.

Syringe simulator

Enter the dose your clinician has prescribed. This only converts units. It doesn't recommend doses.

Mixing table for a 10 mg vial

What each mark on a U-100 insulin syringe holds. With 2 mL of water, for example, the vial holds 5 mg/mL, so every unit is 50 mcg and 10 units is 500 mcg.

WaterStrength1 unit10 units
1 mL10 mg/mL100 mcg1 mg
2 mL5 mg/mL50 mcg500 mcg
3 mL3.333 mg/mL33.33 mcg333.33 mcg
5 mL2 mg/mL20 mcg200 mcg

More water doesn't change the dose, only how much liquid holds it. It makes small doses easier to measure. On a U-100 syringe, 100 units = 1 mL.

How to mix a Semaglutide vial

  1. Wash your hands. Wipe the tops of the peptide vial and the water vial with an alcohol swab and let them dry.
  2. Draw up the amount of bacteriostatic water you've chosen with a fresh syringe.
  3. Push the needle through the rubber top and let the water run slowly down the inside wall, not straight onto the powder.
  4. Swirl or roll the vial gently until the powder dissolves. Don't shake it.
  5. Label the vial with the date and strength, and keep it in the fridge.
  6. Use a new sterile syringe for every dose, and never share needles.

About Semaglutide

How it's taken: Injection under the skin once a week (Ozempic, Wegovy), or a daily tablet (Rybelsus)

How long it lasts (half-life): About 1 week

Storage: Branded pens: refrigerate before first use. Compounded vials: follow pharmacy guidance.

Semaglutide: uses, evidence and side effects

Other Semaglutide vial sizes

Track your Semaglutide vial privately

Fiala is a free app that does this maths for any vial, logs your doses, counts down what's left in each vial and reminds you when a dose is due. No account, and everything you log stays on your phone.

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Not medical advice. This guide only converts units. Double-check every result, and confirm doses and mixing with a pharmacist or clinician.