Fiala
Peptide library › Growth hormone axis
Tesamorelin
Also known as Egrifta
GHRH analog approved to reduce excess abdominal fat in people with HIV-associated lipodystrophy.
What people use it for
- HIV-associated abdominal fat (approved use)
- Visceral fat reduction and body composition (off-label interest)
What Tesamorelin does in the body
A stabilized version of growth hormone–releasing hormone (GHRH). It signals the pituitary to release more of the body's own growth hormone in natural pulses, which raises IGF-1 and preferentially reduces visceral (deep belly) fat.
Strength of evidence
Strong for its approved indication (randomized controlled trials).
Look up the evidence
- Reviews on PubMed: Summaries of the published research
- Clinical trials on PubMed: Published studies in people
- ClinicalTrials.gov: Registered trials, past and ongoing
- Prescribing information (DailyMed, US): Official US label
- Patient leaflets (emc, UK): Official UK product information
Live searches of official databases. New to the terms? See the glossary.
Reported side effects & risks
- Joint pain, muscle aches, swelling
- Injection-site reactions
- Raised blood sugar
- Not for use in pregnancy
Who should avoid it or take extra care
- Pregnant or breastfeeding
- Pituitary surgery, tumour or head radiation
- Active cancer
- Diabetes (it can raise blood sugar; monitoring needed)
Not a complete list. Check with a doctor or pharmacist about your own health and medicines.
Regulatory status
FDA-approved as Egrifta for HIV-associated lipodystrophy.
How it's taken
Route: Injection under the skin once daily
How long it lasts (half-life): About 30 minutes
Mixing guides
How much water to add and what each syringe mark holds, worked out for your own dose:
Latest research & news
- Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review
Research · Review · PubMed · Sex Med Rev · 30 Sept 2026
Picked automatically from PubMed, ClinicalTrials.gov and the FDA, and updated daily. Early, lab and animal studies often don't carry over to people.
Keep track of Tesamorelin privately
Fiala is a free app for logging doses, tracking vials and setting reminders. No account, and everything you log stays on your phone.
Open Tesamorelin in Fiala How to installMore in Growth hormone axis
- SermorelinShort GHRH fragment that stimulates natural growth hormone release.
- CJC-1295Long-acting GHRH analog, often paired with ipamorelin in popular protocols.
- IpamorelinSelective growth hormone secretagogue (ghrelin-receptor agonist).
- HexarelinPotent synthetic growth hormone secretagogue related to GHRP-6.
- GHRP-2Synthetic growth hormone–releasing peptide used in Japan as a diagnostic test.
- GHRP-6First-generation growth hormone–releasing hexapeptide known for strong hunger effects.
- IGF-1 LR3Modified, longer-acting form of insulin-like growth factor 1.
- IGF-1 DESShortened, fast-acting form of insulin-like growth factor 1 sold as a research chemical.
- MK-677Oral growth hormone secretagogue. It is not a peptide, but is commonly tracked alongside them.