Peptide library › Growth hormone axis
CJC-1295
Also known as CJC-1295 with DAC, Mod GRF 1-29 (no DAC)
Long-acting GHRH analog, often paired with ipamorelin in popular protocols.
What people use it for
- Raising growth hormone and IGF-1
- Body composition, recovery and sleep (popular use)
What CJC-1295 does in the body
A modified GHRH analog. The "DAC" (drug affinity complex) version binds to albumin in the blood, extending its action to several days; the version without DAC (Mod GRF 1-29) is short-acting. Both stimulate pituitary growth hormone release.
Strength of evidence
Limited: small early-phase human studies showed sustained rises in GH and IGF-1; clinical development was discontinued.
Look up the evidence
- Reviews on PubMed: Summaries of the published research
- Clinical trials on PubMed: Published studies in people
- ClinicalTrials.gov: Registered trials, past and ongoing
Live searches of official databases. New to the terms? See the glossary.
Reported side effects & risks
- Injection-site reactions
- Flushing, headache
- Water retention
- Theoretical risks of chronically elevated GH/IGF-1
Who should avoid it or take extra care
- Pregnant or breastfeeding
- Active or past cancer
- Diabetes (raised GH and IGF-1 can increase blood sugar)
- Competitive athletes (prohibited by WADA)
Not a complete list. Check with a doctor or pharmacist about your own health and medicines.
Regulatory status
Not approved. Prohibited in sport by WADA.
How it's taken
Route: Injection under the skin
How long it lasts (half-life): About 6–8 days with DAC; about 30 minutes without
Storage
Unreconstituted (powder) vials are usually kept refrigerated or frozen and away from light. Once mixed with bacteriostatic water, keep refrigerated and do not freeze; follow the supplier's stated beyond-use date.
Mixing guides
How much water to add and what each syringe mark holds, worked out for your own dose:
Found in these stacks
- CJC-1295 + Ipamorelin: Two growth hormone releasers that work through different pathways, often sold pre-mixed.
Latest research & news
- Detection of CJC-1295 in Equine Plasma by ELISA
Research · Study · PubMed · Drug Test Anal · 14 Oct 2026 - Peptides in urology and sexual medicine: clinical effectiveness, dosing, indications, and safety: a narrative review
Research · Review · PubMed · Sex Med Rev · 30 Sept 2026
Picked automatically from PubMed, ClinicalTrials.gov and the FDA, and updated daily. Early, lab and animal studies often don't carry over to people.
Keep track of CJC-1295 privately
Fiala is a free app for logging doses, tracking vials and setting reminders. No account, and everything you log stays on your phone.
Open CJC-1295 in Fiala How to installMore in Growth hormone axis
- TesamorelinGHRH analog approved to reduce excess abdominal fat in people with HIV-associated lipodystrophy.
- SermorelinShort GHRH fragment that stimulates natural growth hormone release.
- IpamorelinSelective growth hormone secretagogue (ghrelin-receptor agonist).
- HexarelinPotent synthetic growth hormone secretagogue related to GHRP-6.
- GHRP-2Synthetic growth hormone–releasing peptide used in Japan as a diagnostic test.
- GHRP-6First-generation growth hormone–releasing hexapeptide known for strong hunger effects.
- IGF-1 LR3Modified, longer-acting form of insulin-like growth factor 1.
- IGF-1 DESShortened, fast-acting form of insulin-like growth factor 1 sold as a research chemical.
- MK-677Oral growth hormone secretagogue. It is not a peptide, but is commonly tracked alongside them.