DSIP

What people use it for

• Sleep quality (popular use)
• Stress and withdrawal symptoms (older research)

What DSIP does in the body

First isolated in 1977 from rabbits in induced sleep. How it works is still unclear: it has been reported to affect sleep patterns, stress hormones and pain signalling, but no dedicated receptor has been identified.

Strength of evidence

Weak: small, older studies with inconsistent results.

Look up the evidence

• Reviews on PubMed: Summaries of the published research
• Clinical trials on PubMed: Published studies in people
• ClinicalTrials.gov: Registered trials, past and ongoing

Live searches of official databases. New to the terms? See the glossary.

Reported side effects & risks

• Headache
• Grogginess
• Injection-site reactions
• Limited safety data

Who should avoid it or take extra care

• Pregnant or breastfeeding
• Under 18

Not a complete list. Check with a doctor or pharmacist about your own health and medicines.

Regulatory status

Not approved.

How it's taken

Route: Injection (research and unofficial use)

How long it lasts (half-life): Minutes in the blood

Storage

Unreconstituted (powder) vials are usually kept refrigerated or frozen and away from light. Once mixed with bacteriostatic water, keep refrigerated and do not freeze; follow the supplier's stated beyond-use date.

Mixing guides

How much water to add and what each syringe mark holds, worked out for your own dose:

• 5 mg vial